Cancer in Pregnancy

Cancer is the second leading cause of death in women during the reproductive years. Yet, since the inception of the Motherisk Program in 1985, Motherisk researchers and clinicians have been painfully aware of the lack of data about the management of cancer in pregnancy. To try to address this gap, Motherisk established the Consortium of Cancer in Pregnancy Evidence (CCoPE) to develop up-to-date, evidence-based information on the diagnosis, management, prognosis and fetal outcome of cancer in pregnancy.

Much of the data produced by CCoPE and included in this section of the Motherisk Web site have been published in peer reviewed journals in North America and Europe over the last five years. Some of it, however, is presented here for the first time.

The purpose of this site is to provide a clinically relevant tool for oncologists, obstetrician-gynecologists, perinatologists, neonatologists, family physicians, as well as cancer biologists and other scientists dealing with cancer research. Any clinician or researcher who wishes to contribute to CCoPE's on-going efforts in this field is invited to contact us.

This project is supported by the Lawson Foundation and the Tel Aviv University- HSC Exchange Program, Tel Aviv-Motherisk Advanced Research Project (TAMAR). Motherisk cancer in pregnancy research is also supported by the Susan Westmoreland Legacy Fund.

Specific cancers in pregnancy
Descriptions of specific types of cancer in pregnancy.

Complications during pregnancy
Articles on complications of cancer or cancer treatment during pregnancy.

Radiation in pregnancy
Radiologic modes, effects and estimated average doses to the fetus.

Chemotherapy in pregnancy
List of cytotoxic agents in pregnancy, their source, application, and outcomes in in vitro, animal and human studies.

Fetal Consequences
Neurodevelopment Of Children Exposed In Utero To Treatment For Maternal Malignancy.

Breastfeeding
Chemotherapy and contra indicated drugs during breastfeeding.

Fertility
Study of fertility in children exposed in utero to chemotherapy.

Additional References

Consortium of Cancer in Pregnancy Evidence (CCoPE)
Bios of CCoPE members and Web site contributors.

On-Line Consultative Forum

Site directors:
Gideon Koren, MD, FRCPC, FACCT
Michael Lishner, MD

Site manager:
Motherisk

Disclaimer
The information on the Motherisk/Hospital for Sick Children World Wide Web Site has been developed specifically for The Hospital for Sick Children. It is provided for informational purposes for qualified health care professionals. This material is not intended as a substitute for consulting qualified health care professionals. Patient circumstances will vary and some information may have become outdated as a result of more recent medical developments. The Hospital for Sick Children and Motherisk accept no responsibility for reliance on the information set out in this Web Site.

Reasonable effort has been made to ensure the accuracy of drug doses; however, readers must confirm and follow the doses and schedules set out by manufacturers. The Hospital for Sick Children and Motherisk accept no responsibility for reliance on the drug doses set out herein.