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Be sure to join us for the 11th Annual Fetal Alcohol Canadian Expertise (FACE) Research Roundtable. Program and registration details.
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Current Studies at Motherisk
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Oxycodone while Breastfeeding
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Alcohol Use during Pregnancy
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Control of Hypertension in Pregnancy Study
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Folic Acid Before and During Pregnancy
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Lamisil in Pregnancy
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Meridia in Pregnancy
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Nicotine Replacement Therapy During Pregnancy
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Rheumatoid Arthritis & Arava in Pregnancy
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Severe Morning Sickness
Vitamin A and Congeners
Further Reading
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Lancet. 350(9085):1143-4, 1997 Oct 18.
Shapiro L, Pastuszak A, Curto G, Koren G: Safety of first-trimester exposure to topical tretinoin: prospective cohort study [letter]. -
Ther Drug Monitor 14: 197-202, 1992.
Klein J, Fernandes D, Pastuszak A, Koren, G: Therapeutic drug monitoring of retinoids. -
Koren G: Embryopathy associated with retinoic acid. N Engl J Med 315:262, 1986. -
Reprod Toxicol 8: 63-68, 1994.
Pastuszak AL, Koren G, Rieder MJ: Use of retinoid pregnancy prevention program in Canada: Patterns of contraception use in women treated with the systemic retinoids isotretinoin and etretinate. -
Can Fam Physician 43: 216-219, 1997.
Koren G, Pastuszak A: How to ensure fetal safety when mothers use isotretinoine (Accutane). -
Pastuszak A, Burke B, Koren G: When potent teratogens are irreplaceable drugs: Lessons of thalidomide and isotretinoin. Can J Clin Pharmacol 4/2 (67-73) 1997. -
CMAJ. 1999 Jun 15;160(12):1719-20. No abstract available.
Atanackovic G, Koren G: Fetal exposure to oral isotretinoin: failure to comply with the Pregnancy Prevention Program. -
J Clin Pharmacol. 1998 Oct;38(10):926-30.
Nulman I, Berkovitch M, Klein J, Pastuszak A, Lester RS, Shear N, Koren G: Steady-state pharmacokinetics of isotretinoin and its 4-oxo metabolite: implications for fetal safety. -
Young women taking isotretinoin still conceive: Role of physicians in preventing disaster
Gordana Atanackovic, MD; Gideon Koren, MD, FRCPC -
Is topical tretinoin safe during the first trimester?
Lori Shapiro, MD; Anne Pastuszak, MSC; Giancarla Curto, MD; Gideon Koren, MD, FRCPC -
Fetal alcohol syndrome: Role of the family physician
Gideon Koren, MD, FRCPC; Ronen Loebstein, MD; Irena Nulman, MD













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