Our Helplines
Pregnancy & Breastfeeding Resources
- Morning Sickness
- Drugs in Pregnancy
- Alcohol, Nicotine, Substance Use
- Folic Acid
- Breastfeeding & Drugs
- Cancer in Pregnancy [Forum]
- HIV and HIV Treatment
- Conditions in Pregnancy
- Infectious Diseases in Pregnancy
- Nutrition
- Occupational & Environmental Exposures
- Pharmacokinetics/ Drug Metabolism
- PregTox
- The ReproPsych Group
- CAS Newsletter
Be sure to join us for the 11th Annual Fetal Alcohol Canadian Expertise (FACE) Research Roundtable. Program and registration details.
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- Read more in our News Archive
Current Studies at Motherisk
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Oxycodone while Breastfeeding
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Alcohol Use during Pregnancy
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Control of Hypertension in Pregnancy Study
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Folic Acid Before and During Pregnancy
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Lamisil in Pregnancy
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Meridia in Pregnancy
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Nicotine Replacement Therapy During Pregnancy
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Rheumatoid Arthritis & Arava in Pregnancy
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Severe Morning Sickness
Health Professionals! Click here for Motherisk's free on-line, video tutorial on The Management of Nausea and Vomiting of Pregnancy.
Morning Sickness
Sick of Morning Sickness?Get support from the Motherisk Nausea and Vomiting of Pregnancy (NVP) Helpline.
1-800-436-8477
Nausea and vomiting in pregnancy (NVP), also referred to as "morning sickness," is very common. It afflicts up to 80% of pregnant women, to a greater or lesser extent.
Though usually limited to the first 7 to 12 weeks of pregnancy, approximately 20% of women experience NVP for a longer period of time. Some women may suffer from NVP until the end of the pregnancy.
For some, nausea and vomiting can have serious adverse effects. If severe enough, NVP can cause dehydration, with associated salt and vitamin imbalances. These and other effects can be harmful to the health of the woman and the well-being of her baby. The severity of NVP symptoms can also be related to factors such as a multiple pregnancy.
For these and other reasons, it is important to get the right information, care and treatment.
Nausea and vomiting in pregnancy can also impact on personal relationships. That means that partners and family need information, too.
Care based on research
Motherisk researchers have interviewed thousands of women, gathering detailed accounts of their experience with NVP. Many have describe it as a time of acute suffering, worry and frustration.
This and other research have helped us understand the extent of the suffering, determine possible causes and deterrents, and establish recommendations on how to treat the condition.
We continue to collect information about the effects of NVP and its treatment, paying special attention to NVP's impact on the quality of women's lives.
NVP can and should be treated if persistent or disruptive to a woman's physical, mental or social health.- With a call to the NVP Helpline women can discuss optimal therapies.
- They can also help further Motherisk research by providing information about the effects of NVP on their health and daily lives.
For more information on nausea and vomiting in pregnancy, see these publications and Updates.
Further Reading
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Treatment of nausea and vomiting in pregnancy - an updated algorithm
Adrienne Einarson, RN, Caroline Maltepe, Rada Boskovic, MD and Gideon Koren, MD FRCPC -
Preventing recurrence of severe morning sickness
Gideon Koren, MD, FRCPC, Caroline Maltepe - Ginger can reduce morning sickness in mothers-to-be - MedicalPost.com
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Managing women with nausea and vomiting of pregnancy: Canadian Consensus
G. Klinger, MD; Gideon Koren MD, FRCPC -
Pharmacologic treatment of nausea and vomiting during pregnancy
Paolo Mazzotta, MSC; Abhya Gupta, MD; Antonio Addis, PHARMD; Caroline Maltepe; Gideon Koren, MD, FRCPC; Laura Magee, MD, MSC, FRCPC
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Morning Sickness
Approximately 20% of women experience NVP for a longer period of time. Some women may suffer from NVP until the end of the pregnancy.
Drugs in Pregnancy
Pregnancy, whether planned or a pleasant surprise, brings with it important concerns about prescription and over the counter drugs.
Breastfeeding and Drugs
There are several agents for which safety during breast-feeding is not well-defined and may be a risk to the infant.
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Alcohol, Nicotine, Substance Use
Pregnant? It's never too late to get the facts about alcohol and pregnancy
Conditions in Pregnancy
Exposure to certain infectious diseases during pregnancy may pose a risk to the unborn baby.
Folic Acid
Research shows that women who take vitamins that contain folic acid may lower the risk that their baby will be born with a birth defect called a neural tube defect.
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Nutrition
Good nutrition during pregnancy improves the chances of having a healthy baby who will be at lower risk of diseases.
Infectious Diseases in Pregnancy
Exposure to certain infectious diseases during pregnancy may pose a risk to the unborn baby.
Herbal Products
Natural doesn't always mean safe. But that doesn't stop millions of people, including pregnant women, from consuming naturopathic products.
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Cancer in Pregnancy
Motherisk has been painfully aware of the lack of data about the management of cancer in pregnancy.
HIV and HIV Treatment
It is important that you get tested for HIV. There are many pregnant women who are HIV positive and do not know about it.
Occupational & Environmental Exposures
There are thousands of chemicals in use in today's workplaces - and more women at work than ever before.













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